Biomedical Application of Industrial Microbiology

Recombinant DNA (rDNA) technology advancements over the past few decades have completely changed the field of microbial biotechnology by altering microbial genomes to create cells for the mass manufacture of goods like nutraceuticals and biomedicines. The development of antibiotics and the large-scale manufacture of vaccinations have both been aided by biomedical industrial applications using microbial platforms. Nutraceuticals is a catch-all phrase for pharmaceuticals with bioactive ingredients. Probiotics are made up of bacterial species like Lactobacillus, Bifidobacterium, and others that not only combat harmful bacteria but also generate the body’s vital vitamins (B1, B2, B5, and B6). Novel microbial culture techniques have made it possible to produce in large quantities the bacteria, algae, and yeast that serve as a suitable source of protein in dietary supplements. The manufacture of vaccines today makes use of disease-causing microorganisms that have been attenuated. This chapter will highlight the positive effects of microbial engineering in healthcare and outline the main areas of pharmaceutical biotechnology development.

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Authors and Affiliations

1. Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India Komal Bana & Sachin S. Tiwari

1. Komal Bana